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Irina V Guzhova Selected Research

Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)

2/2021Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress.
5/2020Glyceraldehyde-3-phosphate Dehydrogenase is a Multifaceted Therapeutic Target.
2/2015GAPDH binders as potential drugs for the therapy of polyglutamine diseases: design of a new screening assay.

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Irina V Guzhova Research Topics

Disease

21Neoplasms (Cancer)
11/2021 - 01/2004
6Neuroblastoma
10/2018 - 08/2005
4Melanoma (Melanoma, Malignant)
12/2017 - 05/2013
4Huntington Disease (Huntington's Disease)
06/2017 - 10/2011
3Carcinoma (Carcinomatosis)
06/2021 - 02/2004
3Glioma (Gliomas)
10/2016 - 01/2014
2Alzheimer Disease (Alzheimer's Disease)
10/2021 - 08/2021
2Glioblastoma (Glioblastoma Multiforme)
02/2021 - 11/2014
2Traumatic Brain Injuries (Traumatic Brain Injury)
10/2018 - 01/2018
2Infarction (Infarctions)
04/2016 - 01/2014
2Brain Neoplasms (Brain Tumor)
11/2014 - 01/2014
1Inflammation (Inflammations)
09/2021
1Memory Disorders (Memory Loss)
08/2021
1Colonic Neoplasms (Colon Cancer)
06/2021
1Hypoxia (Hypoxemia)
02/2021
1Pathologic Processes
05/2020
1Neoplasm Metastasis (Metastasis)
12/2019
1Experimental Melanoma
01/2016
1Acute Erythroblastic Leukemia (Erythroleukemia)
03/2015
1Ischemia
01/2014
1Ischemic Stroke
01/2014
1Brain Ischemia (Cerebral Ischemia)
01/2014
1Shock
08/2013
1Atrophy
06/2013
1Seizures (Absence Seizure)
11/2010
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
06/2006
1Sepsis (Septicemia)
01/2006
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2005
1Leukemia
01/2004

Drug/Important Bio-Agent (IBA)

13Proteins (Proteins, Gene)FDA Link
08/2021 - 08/2005
9HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
12/2019 - 01/2006
9Heat-Shock Proteins (Heat-Shock Protein)IBA
04/2016 - 01/2004
5EnzymesIBA
02/2021 - 03/2016
5polyglutamineIBA
01/2018 - 10/2011
4Etoposide (VP 16)FDA LinkGeneric
08/2018 - 01/2004
4Doxorubicin (Adriamycin)FDA LinkGeneric
06/2018 - 01/2004
4Peptides (Polypeptides)IBA
12/2017 - 05/2014
3Glyceraldehyde-3-Phosphate Dehydrogenases (GAPD)IBA
02/2021 - 02/2015
3Pharmaceutical PreparationsIBA
06/2018 - 12/2007
2CytokinesIBA
10/2021 - 12/2019
2Amyloid (Amyloid Fibrils)IBA
10/2021 - 08/2021
2CaspasesIBA
09/2021 - 01/2004
2Cadherins (E-Cadherin)IBA
06/2021 - 04/2016
2bovine collectin-43 proteinIBA
06/2021 - 06/2018
2Hydrocortisone (Cortisol)FDA LinkGeneric
10/2018 - 01/2018
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
03/2016 - 02/2016
2Small Interfering RNA (siRNA)IBA
10/2011 - 12/2007
21- (6- ((3- methoxyestra- 1,3,5(10)- trien- 17- yl)amino)hexyl)- 1H- pyrrole- 2,5- dioneIBA
06/2006 - 02/2004
2Type C PhospholipasesIBA
06/2006 - 02/2004
1Neuroprotective AgentsIBA
10/2021
1LigandsIBA
08/2021
1Transcription Factors (Transcription Factor)IBA
06/2021
12-phenylacetylenesulfonamideIBA
06/2021
1Messenger RNA (mRNA)IBA
06/2021
1Glucose (Dextrose)FDA LinkGeneric
06/2021
1cobaltous chloride (cobalt(II)chloride)IBA
02/2021
1Caspase 3 (Caspase-3)IBA
08/2018
1Cisplatin (Platino)FDA LinkGeneric
06/2018
1CardenolidesIBA
06/2018
1ProdrugsIBA
06/2018
1Therapeutic UsesIBA
01/2018
1Drug CombinationsIBA
01/2018
1Cytostatic AgentsIBA
12/2017
1Peptide FragmentsIBA
12/2017
1PrionsIBA
06/2017
1VaccinesIBA
10/2016
1Neoplasm Antigens (Tumor Antigens)IBA
10/2016
1Metalloproteases (Metalloproteinases)IBA
04/2016
1Glyceraldehyde 3-Phosphate (Glyceraldehyde 3 Phosphate)IBA
03/2016
1Huntingtin ProteinIBA
03/2016
1Oxidoreductases (Dehydrogenase)IBA
03/2016
1triptolideIBA
02/2016
1PhloretinIBA
01/2016
1Membrane LipidsIBA
03/2015
1AvidinIBA
03/2015
1Granzymes (Granzyme)IBA
11/2014
1Interferon-gamma (Interferon, gamma)IBA
11/2014
1Adenosine Triphosphatases (ATPase)IBA
05/2014
1Annexin A5IBA
01/2014
1ChloridesIBA
01/2014
1AlginatesIBA
01/2014
1HydrogelsIBA
05/2013
1Cancer VaccinesIBA
05/2013
1Mutant Proteins (Protein, Mutant)IBA
10/2011
1N-Methylaspartate (NMDA)IBA
11/2010
1Pentylenetetrazole (Metrazol)IBA
11/2010
1CamptothecinIBA
12/2007
1Estrogen ReceptorsIBA
12/2007
1ErbB Receptors (EGF Receptor)IBA
12/2006
1Protein AggregatesIBA
08/2005

Therapy/Procedure

10Therapeutics
11/2021 - 05/2013
3Immunotherapy
10/2016 - 11/2014
2Injections
01/2014 - 11/2010
1Ligation
04/2016
1Catheters
01/2014